张文科

男， 吉林大学超分子结构与材料全国重点实验室， 教授/研究员/教授级高工或同等级别

学习/工作经历

1993.09-1997.07，吉林大学化学系，本科生
1997.09-2002.07，吉林大学化学学院，研究生（硕博连读）
2001.04-2002.03，德国慕尼黑大学应用物理系，博士生联合培养
2003.03-2004.09，英国诺丁汉大学药学院，博士后
2004.10-2007.05，英国诺丁汉大学化学学院，博士后
2007.06-至今，吉林大学超分子结构与材料国家重点实验室，教授

研究领域和兴趣

聚合物单分子力谱与超分子相互作用，高分子结晶与熔融，纳米药物递送，高分子力化学

主要业绩

长期从事聚合物单分子力谱研究，近年来在高分子凝聚态体系的分子间相互作用及超分子组装推动力研究方面取得一系列重要的创新性成果，部分成果发表在Nat. Commun.，J. Am. Chem. Soc. 等重要国际期刊上，并受到国际同行的广泛关注与积极评价。应邀在国际国内重要学术会议做邀请报告30余次（其中包括3次大会报告）。2015年获得国家杰出青年科学基金获资助，2017年入选科技部“创新人才推进计划”中青年科技创新领军人才，2018年入选中组部“万人计划”领军人才。主持国家重大科研仪器研制项目（自由申请）及基金委面上等项目。担任luck18首页高分子学科委员会、生物物理化学专业委员会、超分子化学专业委员会委员，AIMS Biophysics及Langmuir期刊编委。

代表成果

[1] Wenke Zhang; Ziwen Ma; Yuanfei Jiang; Wei Feng; Yu Song; SINGLE-MOLECULE FORCE SPECTROSCOPY-INFRARED SPECTROSCOPY (SMFS-IR) COUPLING METHOD AND SYSTEM, AND DEVICE; 2024, 18/968553; 2025, US 12320826B1 (美国专利)
[2] X. Zhang, H. Zhang, S. Lu, Y. Song*, W. K. Zhang*, Direct detection of the chain trajectory and long-range correlation in crystalline−amorphous polymer networks by single-molecule force spectroscopy, Macromolecules, 2025, 58, 6170−6177. DOI: 10.1021/acs.macromol.5c01007
[3] Y. Song, Z. Ma, W. K. Zhang*, Manipulation of a single polymer chain: from the nanomechanical properties to dynamic structure evolution, Macromolecules, 2022, 55, 4177−4199. DOI: 10.1021/acs.macromol.2c00076 (Invited Perspective, ACS Editors’ Choice)
[4] X. N. Zhang, X. Kou, W. Zhang, W. K. Zhang*, Identification of the new type of G-Quadruplex with multiple vacant sites in human telomeric DNA, CCS Chem., 2022, 4, 3023–3035. DOI: 10.31635/ccschem.021.202101436
[5] X. N. Zhang, Y. Q. Zhang and W. K. Zhang*, Dynamic topology of double-stranded telomeric DNA studied by single-molecule manipulation in vitro, Nucleic Acids Res., 2020, 48, 6458–6470. DOI: 10.1093/nar/gkaa479
[6] Z. W. Ma, P. Yang, X. Y. Zhang, K. Jiang, Y. Song*, W. K. Zhang*, Quantifying the chain folding in polymer single crystals by single-molecule force spectroscopy, ACS Macro Lett., 2019, 8, 1194−1199. DOI: 10.1021/acsmacrolett.9b00607 (ACS Editors’ Choice)
[7] H. Zhang, X. Li, Y. J. Lin, F. Gao, Z. Tang, P. F. Su, W. K. Zhang*, Y. Z. Xu, W. G. Weng*, R. Boulatov*, Multi-modal mechanophores based on cinnamate dimers, Nat. Commun., 2017, 8, 1147. DOI: 10.1038/s41467-017-01412-8
[8] Y. R. Xue, X. Li, H. B. Li, W. K. Zhang*, Quantifying thiol-gold interactions towards the efficient strength control, Nat. Commun., 2014, 5:4348. DOI: 10.1038/ncomms5348
[9] N. N. Liu, B. Peng, Y. Lin, Z. H. Su, Z. W. Niu, Q. Wang, W. K. Zhang*, H. B. Li, J. C. Shen, Pulling genetic RNA out of tobacco mosaic virus using single-molecule force spectroscopy, J. Am. Chem. Soc., 2010, 132, 11036-11038. DOI:10.1021/ja1052544
[10] K. Liu, Y. Song, W. Feng, N. N. Liu, W. K. Zhang*, X. Zhang, Extracting a single polyethylene oxide chain from a single crystal by a combination of atomic force microscopy imaging and single-molecule force spectroscopy: toward the investigation of molecular interactions in their condensed states, J. Am. Chem. Soc., 2011, 133, 3226-3229. DOI: 10.1021/ja108022h (Highlighted by Nature Materials)

*以上信息由高级会员个人更新和维护。